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Jason Paxman

La Trobe Institute for Molecular Science, Australia

Biography

Jason Paxman is a senior postdoctoral researcher within the group led by Dr Begoña Heras within the Department of Biochemistry and Genetics at the La Trobe Institute for Molecular Science, Melbourne Australia. He has a strong interest in deciphering the mechanisms of action of bacterial virulence factors using X-ray crystallography. During his PhD at Monash University Australia he revealed for the first time how DsbA, a key bacterial virulence regulator, binds and folds a plethora of bacterial virulence factors. Past appointments include the Commonwealth Scientific and Industrial Research Organisation, The University of Melbourne and the Australian Synchrotron. Career highlights include developing anti-anthrax agents for the U.S. Department of Defence and being awarded an Australian Synchrotron Research Fellowship. His current work includes determining the mechanisms of action for one of the largest groups of bacterial virulence factors, the autotransporters.

Abstract

Abstract : Using protein crystallography to disarm bacterial pathogens